Publications

Technologies bringing young Zebrafish from a niche field to the limelight

Jason J Otterstrom, Alexandra Lubin, Elspeth M Payne, Yael Paran
SLAS Technol. 2022 Apr;27(2):109-120. doi: 10.1016/j.slast.2021.12.005

Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis.

Ferrada MA, Savic S, Cardona DO, Collins JC, Alessi H, Gutierrez-Rodrigues F, Kumar DBU, Wilson L, Goodspeed W, Topilow JS, Paik JJ, Poulter JA, Kermani TA, Koster MJ, Warrington KJ, Cargo C, Tattersall RS, Duncan CJA, Cantor A, Hoffmann P, Payne EM, Bonnekoh H, Krause K, Cowen EW, Calvo KR, Patel BA, Ombrello AK, Kastner DL, Young NS, Werner A, Grayson PC, Beck DB.
Blood. 2022 Sep 29;140(13):1496-1506. 

Antibody responses to SARS-CoV-2 vaccination in patients with acute myeloid leukaemia and high risk MDS on active anti-cancer therapies

Wei Yee Chan, Catherine Zhu, Emilie Sanchez, Rajeev Gupta, Adele K. Fielding, Asim Khwaja, *Elspeth M. Payne,*Jenny O'Nions. 
Br J Haematol. 2022 Aug;198(3):478-481

SARS-CoV-2 infection in aplastic anaemia.

Avenoso D, Marsh JCW, Potter V, Pagliuca A, Slade S, Dignan F, Tholouli E, Mittal S, Davis B, Tauro S, Kesse-Adu R, Griffin M, Payne E, Gandhi S, Kulasekararaj AG.
Haematologica. 2021.

Guidelines for the diagnosis and evaluation of prognosis of adult myelodysplastic syndromes

SB Killick, W Ingram, D Culligan, H Enright, J Kell, E Payne, P Krishnamurthy, A Kulasekararaj, M Raghavan, S J Stanworth, S Green, G Mufti, L Quek, C Cargo, GL Jones, J Mills, A Sternberg, D Wiseman, and D Bowen . 
 Br J Haematol. 2021;194(2):282-93.

Guidelines for the Management  Adult Myelodysplastic Syndromes

SB Killick, D Wiseman, L Quek, C Cargo, D Culligan, H Enright, S Green, W Ingram, GL Jones, J Kell, P Krishnamurthy, A Kulasekararaj, J Mills1, G Mufti, E Payne, M Raghavan, S J Stanworth, A Sternberg, and D Bowen.  
Br J Haematol. 2021;194(2):267-81

Differential Requirement of Gata2a and Gata2b for Primitive and Definitive Myeloid Development in Zebrafish

Oscar A. Peña, Alexandra Lubin, Jasmine Rowell, Yvette Hoade, Noreen Khokhar, Hanna Lemmik, Christopher Mahony, Phoebe Dace, Chianna Umamahesan and Elspeth M. Payne
Front. Cell Dev. Biol., 13 September 2021; doi.: 10.3389/fcell.2021.708113

A versatile, automated and high-throughput drug screening platform for zebrafish embryos

Alexandra Lubin , Jason Otterstrom, Yvette Hoade, Ivana Bjedov , Eleanor Stead, Matthew Whelan , Gaia Gestri, Yael Paran, Elspeth Payne
Biol Open​ 2021 Sep 15;10(9):bio058513. doi: 10.1242/bio.058513.

TLR7 ligation augments haematopoiesis in Rps14 (uS11) deficiency via paradoxical suppression of inflammatory signalling and enhanced differentiation

Oscar A Peña, Alexandra Lubin, Jasmine Rowell, Catherine Hockings, Youngrock Jung, Yvette Hoade, Phoebe Dace, Leonardo E Valdivia, Karin Tuschl, Charlotta Boiers, Maria C Virgilio, Simon Richardson, Elspeth M Payne
bioRxiv 2020.07.06.175000; doi: https://doi.org/10.1101/2020.07.06.175000

Successful use of allogeneic bone marrow transplantation in a patient with myelodysplastic syndrome presenting with autoimmune manifestations.

Simini, G., Mackenzie, S., Gohil, S., Papanikolaou, X., Manson, J. and Payne, EM.
Br J Haematol. 2021;193(6):1275-7.

In Trans Early Mosaic Mutational Escape and Novel Phenotypic Features of Germline SAMD9 Mutation

Hockings C, Gohil S, Dowse R, et al.
Br J Haematol. 2020;188(4):e53–e57.

DNAJC21 mutations link a cancer prone bone marrow failure syndrome to corruption in 60S ribosome subunit maturation

Hemanth Tummala, Amanda J Walne, Mike Williams, Nicholas Bockett, Laura Collopy, Shirleny Cardoso, Alicia Ellison, Rob Wynn,  Thierry Leblanc, Jude Fitzgibbon,  David P Kelsell, David A van Heel, Elspeth Payne, Vincent Plagnol, Inderjeet Dokal* and Tom Vulliamy*
Am J Hum Genet. 2016 Jul 7;99(1):115-24.

L-leucine improves the anemia in models of Diamond-Blackfan anemia and the 5q- syndrome in a p53-independent way

Anupama Narla*, Elspeth Payne*, Nirmalee Abayasekara et al.
Br J Haematol. 2014 Aug 7

Molecular Basis of Cancer. Ch 8  Mendelsohn at al 4th Edition 2014 (3rd edition 2008)

E Payne and A Thomas Look

Advances in Hematology, Special Issue on The Zebrafish as a Tool to Study Hematopoiesis, Human Blood Diseases and Immune Function

Berman J, Payne E, Hall C.
Adv Hematol. Oct 2012:425345. 2012

L-Leucine Improves the Anemia and Developmental Defects Associated With Diamond-Blackfan Anemia and del(5q) MDS by Activating the mTOR Pathway

Payne EM, Virgilio M, Narla A, et al.
Blood. 2012 Sep 13;120(11):2214-24.

Myelopoiesis and myeloid leukaemogenesis in the zebrafish

Forrester AM, Berman JN, Payne EM.
Adv Hematol. July 2012;2012:358518.

 

NUP98-HOXA9-transgenic zebrafish develop a myeloproliferative neoplasm and provide new insight into mechanisms of myeloid leukaemogenesis

Forrester AM, Grabher C, McBride ER, Boyd ER, Vigerstad MH, Edgar A, Kai FB, Da'as SI, Payne E, Look AT, Berman JN.
Br J Haematol. 2011 Oct;155(2):167-81.

 

Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia

Gutierrez A, Grebliunaite R, Feng H, Kozakewich E, Zhu S, Guo F, Payne E, Mansour M, Dahlberg SE, Neuberg DS, den Hertog J, Prochownik EV, Testa JR, Harris M, Kanki JP, Look AT.
J Exp Med. 2011 Aug 1;208(8):1595-603.

 

Ddx18 is essential for cell cycle progression in zebrafish hematopoietic cells and is mutated in human acute myeloid leukemia

Payne EM, Bolli N, Rhodes J,  et al.
Blood. 2011 Jul 28;118(4):903-15.

 

Cpsf1 is required for definitive hematopoietic stem cell survival in zebrafish

Bolli N, Payne EM, Rhodes J, et al.
Blood. 2011 Apr 14;117(15):3996-4007.

 

Endothelial Von Willebrand Factor Regulates Angiogenesis

Starke RD, Ferraro F, Paschalaki KE, Dryden NH, McKinnon TA, Sutton RE, Payne EM, Haskard DO, Hughes AD, Cutler DF, Laffan MA, Randi AM.
Blood. 2011 Jan 20;117(3):1071-80.

 

Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of primitive myeloid cells and definitive hematopoietic stem cells in zebrafish

Grabher C*, Payne EM*, Johnston AB, et al. Leukemia. 2011 Mar;25(3):506-14*co-first authors
Bolli N*, Payne EM*, Grabher C, et al.
Blood 2010 Apr 22;115(16):3329-40.

 

Zebrafish Modeling of Leukaemias

Elspeth Payne and A Thomas Look.
Br J Haematol. 2009 Aug;146(3):247-5609

 

Clinical Effects and P-glycoprotein Inhibition in Patients With Acute Myeloid Leukemia Treated With Zosuquidar Trihydrochloride, Daunorubicin and Cytarabine

Gerrard G,  Payne E, Ganeshaguru K, et al.
Hematologica 2004 July;89(7): 782-90

Effect of anti-CD20 (Rituximab) on resistant thrombocytopenia in Autoimmune Lymphoproliferative Syndrome

Heelan B, Torney V, Amlot P, Payne E, Mehta A, Puck J, Webster ABD.
British Journal of Haematology Sep 2002; 118(4): 1078-81