Publications
Hemanth Tummala, Amanda J Walne, Mike Williams, Nicholas Bockett, Laura Collopy, Shirleny Cardoso, Alicia Ellison, Rob Wynn, Thierry Leblanc, Jude Fitzgibbon, David P Kelsell, David A van Heel, Elspeth Payne, Vincent Plagnol, Inderjeet Dokal* and Tom Vulliamy*. DNAJC21 mutations link a cancer prone bone marrow failure syndrome to corruption in 60S ribosome subunit maturation. Am J Hum Genet. 2016 Jul 7;99(1):115-24.
Anupama Narla*, Elspeth Payne*, Nirmalee Abayasekara et al. L-leucine improves the anemia in models of Diamond-Blackfan anemia and the 5q- syndrome in a p53-independent way. Br J Haematol. 2014 Aug 7
E Payne and A Thomas Look : Molecular Basis of Cancer. Ch 8 Mendelsohn at al 4th Edition 2014 (3rd edition 2008)
Berman J, Payne E, Hall C. Advances in Hematology, Special Issue on The Zebrafish as a Tool to Study Hematopoiesis, Human Blood Diseases and Immune Function. Adv Hematol. Oct 2012:425345. 2012
* Payne EM, Virgilio M, Narla A, et al. Treatment of L-Leucine in zebrafish models of ribosomopathies (Diamond Blackfan Anemia (DBA) and MDS5q) results in an improvement of anemia and developmental defects: evidence for a common pathway? Blood. 2012 Sep 13;120(11):2214-24. *corresponding author
Forrester AM, Berman JN, Payne EM. Myelopoiesis and myeloid leukaemogenesis in the zebrafish
Adv Hematol. July 2012;2012:358518.
Forrester AM, Grabher C, McBride ER, Boyd ER, Vigerstad MH, Edgar A, Kai FB, Da'as SI, Payne E, Look AT, Berman JN. NUP98-HOXA9-transgenic zebrafish develop a myeloproliferative neoplasm and provide new insight into mechanisms of myeloid leukaemogenesis. Br J Haematol. 2011 Oct;155(2):167-81.
Gutierrez A, Grebliunaite R, Feng H, Kozakewich E, Zhu S, Guo F, Payne E, Mansour M, Dahlberg SE, Neuberg DS, den Hertog J, Prochownik EV, Testa JR, Harris M, Kanki JP, Look AT. Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia. J Exp Med. 2011 Aug 1;208(8):1595-603.
* Payne EM, Bolli N, Rhodes J, et al. Ddx18 is essential for cell cycle progression in zebrafish hematopoietic cells and is mutated in human acute myeloid leukemia. Blood. 2011 Jul 28;118(4):903-15. *corresponding author
Bolli N, Payne EM, Rhodes J, et al. Cpsf1 is required for definitive hematopoietic stem cell survival in zebrafish. Blood. 2011 Apr 14;117(15):3996-4007.
Starke RD, Ferraro F, Paschalaki KE, Dryden NH, McKinnon TA, Sutton RE, Payne EM, Haskard DO, Hughes AD, Cutler DF, Laffan MA, Randi AM.. Endothelial Von Willebrand Factor Regulates Angiogenesis. Blood. 2011 Jan 20;117(3):1071-80.
Grabher C*, Payne EM*, Johnston AB, et al. Leukemia. 2011 Mar;25(3):506-14*co-first authors
Bolli N*, Payne EM*, Grabher C, et al. Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of primitive myeloid cells and definitive hematopoietic stem cells in zebrafish. Blood 2010 Apr 22;115(16):3329-40. Elspeth Payne and A Thomas Look. Zebrafish Modeling of Leukaemias. Br J Haematol. 2009 Aug;146(3):247-5609
Gerrard G, Payne E, Ganeshaguru K, et al. Clinical response and inhibition of P-gp activity in patients with AML treated with zosuquidar trihydrochloride in combination with daunorubicin and cytarabine. Hematologica 2004 July;89(7): 782-90
Heelan B, Torney V, Amlot P, Payne E, Mehta A, Puck J, Webster ABD. Effect of anti-CD20 (Rituximab) on resistant thrombocytopenia in Autoimmune Lymphoproliferative Syndrome. British Journal of Haematology Sep 2002; 118(4): 1078-81