Publications
TLR7 ligation augments haematopoiesis in Rps14 (uS11) deficiency via paradoxical suppression of inflammatory signalling and enhanced differentiation
Oscar A Peña, Alexandra Lubin, Jasmine Rowell, Catherine Hockings, Youngrock Jung, Yvette Hoade, Phoebe Dace, Leonardo E Valdivia, Karin Tuschl, Charlotta Boiers, Maria C Virgilio, Simon Richardson, Elspeth M Payne
bioRxiv 2020.07.06.175000; doi: https://doi.org/10.1101/2020.07.06.175000
In Trans Early Mosaic Mutational Escape and Novel Phenotypic Features of Germline SAMD9 Mutation
Hockings C, Gohil S, Dowse R, et al.
Br J Haematol. 2020;188(4):e53–e57.
DNAJC21 mutations link a cancer prone bone marrow failure syndrome to corruption in 60S ribosome subunit maturation
Hemanth Tummala, Amanda J Walne, Mike Williams, Nicholas Bockett, Laura Collopy, Shirleny Cardoso, Alicia Ellison, Rob Wynn, Thierry Leblanc, Jude Fitzgibbon, David P Kelsell, David A van Heel, Elspeth Payne, Vincent Plagnol, Inderjeet Dokal* and Tom Vulliamy*
Am J Hum Genet. 2016 Jul 7;99(1):115-24.
L-leucine improves the anemia in models of Diamond-Blackfan anemia and the 5q- syndrome in a p53-independent way
Anupama Narla*, Elspeth Payne*, Nirmalee Abayasekara et al.
Br J Haematol. 2014 Aug 7
Molecular Basis of Cancer. Ch 8 Mendelsohn at al 4th Edition 2014 (3rd edition 2008)
E Payne and A Thomas Look
Advances in Hematology, Special Issue on The Zebrafish as a Tool to Study Hematopoiesis, Human Blood Diseases and Immune Function
Berman J, Payne E, Hall C.
Adv Hematol. Oct 2012:425345. 2012
L-Leucine Improves the Anemia and Developmental Defects Associated With Diamond-Blackfan Anemia and del(5q) MDS by Activating the mTOR Pathway
Payne EM, Virgilio M, Narla A, et al.
Blood. 2012 Sep 13;120(11):2214-24.
Myelopoiesis and myeloid leukaemogenesis in the zebrafish
Forrester AM, Berman JN, Payne EM.
Adv Hematol. July 2012;2012:358518.
NUP98-HOXA9-transgenic zebrafish develop a myeloproliferative neoplasm and provide new insight into mechanisms of myeloid leukaemogenesis
Forrester AM, Grabher C, McBride ER, Boyd ER, Vigerstad MH, Edgar A, Kai FB, Da'as SI, Payne E, Look AT, Berman JN.
Br J Haematol. 2011 Oct;155(2):167-81.
Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia
Gutierrez A, Grebliunaite R, Feng H, Kozakewich E, Zhu S, Guo F, Payne E, Mansour M, Dahlberg SE, Neuberg DS, den Hertog J, Prochownik EV, Testa JR, Harris M, Kanki JP, Look AT.
J Exp Med. 2011 Aug 1;208(8):1595-603.
Ddx18 is essential for cell cycle progression in zebrafish hematopoietic cells and is mutated in human acute myeloid leukemia
Payne EM, Bolli N, Rhodes J, et al.
Blood. 2011 Jul 28;118(4):903-15.
Cpsf1 is required for definitive hematopoietic stem cell survival in zebrafish
Bolli N, Payne EM, Rhodes J, et al.
Blood. 2011 Apr 14;117(15):3996-4007.
Endothelial Von Willebrand Factor Regulates Angiogenesis
Starke RD, Ferraro F, Paschalaki KE, Dryden NH, McKinnon TA, Sutton RE, Payne EM, Haskard DO, Hughes AD, Cutler DF, Laffan MA, Randi AM.
Blood. 2011 Jan 20;117(3):1071-80.
Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of primitive myeloid cells and definitive hematopoietic stem cells in zebrafish
Grabher C*, Payne EM*, Johnston AB, et al. Leukemia. 2011 Mar;25(3):506-14*co-first authors
Bolli N*, Payne EM*, Grabher C, et al.
Blood 2010 Apr 22;115(16):3329-40.
Zebrafish Modeling of Leukaemias
Elspeth Payne and A Thomas Look.
Br J Haematol. 2009 Aug;146(3):247-5609
Clinical Effects and P-glycoprotein Inhibition in Patients With Acute Myeloid Leukemia Treated With Zosuquidar Trihydrochloride, Daunorubicin and Cytarabine
Gerrard G, Payne E, Ganeshaguru K, et al.
Hematologica 2004 July;89(7): 782-90
Effect of anti-CD20 (Rituximab) on resistant thrombocytopenia in Autoimmune Lymphoproliferative Syndrome
Heelan B, Torney V, Amlot P, Payne E, Mehta A, Puck J, Webster ABD.
British Journal of Haematology Sep 2002; 118(4): 1078-81